pentobarbital will minimize the level or outcome of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of abemaciclib with powerful CYP3A4 inducers minimizes plasma focus of abemaciclib and its metabolites.Pentobarbital belongs to a category of drugs known as barbiturates whi